Matthew Long (firefighter)

Matthew Long (born 1966) is a New York City firefighter who was hit by a charter bus on December 22, 2005 while riding his bicycle to work during a transit worker strike.[1] His injuries were nearly fatal.[2] Long recovered from his injuries, and was included on the list of the world’s 25 fittest men published by Men’s Fitness in 2010. Despite suffering chronic pain and his right leg being slightly shorter than his left he completed the New York City Marathon in 2008 in a time of seven hours, 21 minutes.[2]
He published his first book, The Long Run: A New York City Firefighter’s Triumphant Comeback from Crash Victim to Elite Athlete in 2010 (ISBN 160529246X). It was co-authored by Charles Butler.
Long appeared on The Daily Show with Jon Stewart on August 16, 2011 to promote his book.[3]
References[edit]

^ Charles Butler (March 2009). “Matt Long’s Second Life”. Runners World. Retrieved 2012-03-17. 
^ a b Jennifer Fermino (2010-03-22). “Fireman who almost died is now in buff elite”. New York Post. Retrieved 2012-03-17. 
^ “Matt Long”. Comedy Central. 11 August 2009. Retrieved 2015-10-20. 

WKAK

WKAK

City
Albany, Georgia

Broadcast area
Albany, GA and Vicinity

Branding
Nash FM 104.5

Slogan
“Today’s Best Country And Your All Time Favorites”

Frequency
104.5 MHz

First air date
1963

Format
Modern Country

ERP
98,000 watts

HAAT
299 meters

Class
C1

Facility ID
831

Owner
Cumulus Media
(Cumulus Licensing LLC)

Sister stations
WALG, WEGC, WGPC, WJAD, WNUQ, WQVE

Webcast
Listen Live

Website
kcountry104.com

WKAK (branded as Nash FM 104.5) is a radio station serving Albany, Georgia and surrounding cities with a modern country format. This station broadcasts on FM frequency 104.5 MHz and is under ownership of Cumulus Media.
WKAK programming includes Tony and Chris in the AM, John Blake in Mid-days, Cazper in the afternoons and Nash Nights Live with Shawn Parr.
External links[edit]

Nash FM 104.5 – Official Website

Query the FCC’s FM station database for WKAK
Radio-Locator information on WKAK
Query Nielsen Audio’s FM station database for WKAK

v
t
e

Radio stations in the Albany, Georgia market

By FM frequency

89.3
90.3
90.7
91.7
93.1
93.9
94.7
96.3
97.3
98.1
100.3
101.7
102.1
103.5
104.5
105.5
106.1
106.5
107.7

By AM frequency

960
1250
1450
1590

By callsign

WAEF
WALG
WBJY
WDEC
WEGC
WGEX
WGPC
WHKV
WJAD
WJIZ-FM
WJYZ
WKAK
WMRZ
WMTM-FM
WNUQ
WOBB
WQVE
WSRA
WSRD-LP
WUNV
WWQA
WZBN
WZIQ

Georgia radio markets
Albany
Atlanta
Augusta
Brunswick
Columbus
Macon
Savannah
Valdosta

Other Georgia radio regions
Rome
Thomasville/Bainbridge
Waycross

See also
List of radio stations in Georgia
List of radio stations in Florida
Tallahassee Radio

v
t
e

Country radio stations in the state of Georgia

Stations

WAAC – Valdosta
WAJQ-FM – Alma
WBAF – Barnesville
WBTR-FM – Carrollton
WBYZ – Baxley
WCJM-FM – West Point
WCOH – Newnan
WCON – Cornelia
WCON-FM – Cornelia
WDAL – Dalton
WDEN – Macon
WEKS – Zebulon
WFDR – Manchester
WFFM – Ashburn
WGCO – Midway/Savannah
WHIE – Griffin
WHKN – Millen
WIFO – Jesup
WIHB – Macon
WIHB-FM – Gray
WISK-FM – Americus
WJCL-FM – Savannah
WJTH – Calhoun
WKAA – Willacoochee
WKAK – Albany
WKBX – Kingsland
WKCN – Lumpkin
WKHX – Marietta
WKKP – McDonough
WKLY – Hartwell
WKNG – Tallapoosa
WKUB – Blackshear
WKZR – Milledgeville
WKZZ – Tifton
WLHR – Lavonia
WLJA – Ellijay
WLUB – Augusta
WLYU – Lyons
WMCG – Milan
WMNZ – Montezuma
WMOQ – Bostwick
WNGC – Toccoa
WOBB – Tifton
WOKA-FM

Persona 2

Persona 2 may refer to:

Persona 2: Innocent Sin, a 1999 video game
Persona 2: Eternal Punishment, a 2000 video game

This set index page lists media articles associated with the same name, and/or related to the same original work.
If an internal link led you here, you may wish to change the link to point directly to the intended article.

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Acrosin

Acrosin

Identifiers

EC number
3.4.21.10

CAS number
9068-57-9

Databases

IntEnz
IntEnz view

BRENDA
BRENDA entry

ExPASy
NiceZyme view

KEGG
KEGG entry

MetaCyc
metabolic pathway

PRIAM
profile

PDB structures
RCSB PDB PDBe PDBsum

Gene Ontology
AmiGO / EGO

Search

PMC
articles

PubMed
articles

NCBI
proteins

Acrosin is a digestive enzyme that acts as a protease. In humans, acrosin is encoded by the ACR gene.[1][2] Acrosin is released from the acrosome of spermatozoa as a consequence of the acrosome reaction. It aids in the penetration of the Zona Pellucida.

Contents

1 Enzyme Mechanism
2 Biological Function
3 Structure
4 Disease and Pharmaceutical Relevance
5 References
6 Further reading
7 External links

Enzyme Mechanism[edit]
Acrosin is a typical serine proteinase with trypsin-like specificity.[3]

Acrosin catalytic mechanism

The reaction proceeds according to the usual serine protease mechanism. First, His-57 deprotonates Ser-195, allowing it to serve as a nucleophile. Deprotonated Ser-195 then reacts with the carbonyl carbon of a peptide, forming a tetrahedral intermediate. The tetrahedral intermediate then collapses, resulting in an H2N-R1 leaving group, which is protonated through His-57. Finally, His-57 deprotonates a water molecule, which can then serve as a nucleophile by similarly reacting with the carbonyl carbon. Collapse of the tetrahedral intermediate then results in a Ser-195 leaving group, which is protonated through His-57, resulting in all residues returned to their pre-catalytic state, and a carboxylic acid where there was previously a peptide bond.
Biological Function[edit]
Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is stored in the acrosome in its precursor form, proacrosin. Upon stimulus, the acrosome releases its contents onto the zona pellucida. After this reaction occurs, the zymogen form of the protease is then processed into its active form, β-acrosin. The active enzyme then functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum.[3]
The importance of acrosin in the acrosome reaction has been contested. It has been found through genetic knockout experiments that mouse spermatozoa lacking β-acrosin (the active protease) still have the ability to penetrate the zona pellucida.[4] Thus, some argue for its role in assisting in the dispersal of acrosomal contents fo
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